Welcome to the
Microbial Spatial Gene regulation Lab
Mission of the lab
Our research explores how the spatiotemporal control of gene expression shapes microbial cell physiology and differentiation
By integrating high-resolution imaging techniques, molecular biology and genetics, we investigate gene regulation in single fungal and bacterial cells, aming to understand how single cells adopt both individual and collective strategies to optimize their fitness
We love microbes!
S. cerevisiae
Filamentous S. cerevisiae
Candida albicans
Arbuscular mycorrhizal fungi
Aspergillus niger
E. coli
We are always open to explore the physiology of new microorganisms. Contact us for collaborations!
1 - Methods development for RNA visualization and imaging analysis in fixed microbial cells based on single molecule RNA FISH (smFISH)
smFISH-IF in S. cerevisiae
2 - Methods development for RNA imaging in live microbial cells based on the MS2 and PP7 systems
Live imaging MS2 tagged mRNAs Maekiniemi et al. 2024
3 - Regulation of filamentous fungi differentiation and biofilm formation
Candida albicans
4 - RNA localization and spatial control of protein synthesis
5 - Regulation of mRNA degradation in S. cerevisiae
6 - Development of imaging analysis pipelines for microbial species
Questions?
Contact evelina.tutucci[at]vu.nl to get more information on the projects
Support:
